Launch the next era of proteomics​

Answer your most complex biological questions, streamline your novel multiomics insights, accelerate your next proteomics discovery. Introducing Illumina Protein Prep, an end-to-end NGS research solution for protein quantification of 9500 unique human proteins, powered by SOMAmer® technology.​
Prepare yourself for the next era of multiomic breakthroughs.

Why NGS-based proteomics?

What are the key applications in proteomics research enabled by NGS-based high-throughput protein detection?

NGS-based proteomics enables these key

applications in human disease research,

deepening insights by integrating proteomic

data to accelerate your next multiomic

breakthrough:​

- Biomarker Discovery​
​- Drug Target Identification​
- Precision Medicine​
- Disease Pathobiology​
- Population-level omics

How would I tackle data analysis on the vast amounts of proteomic data that would be generated?

To address data analysis, Illumina Protein Prep solution includes data analysis software, for normalization and quantification of proteins, enabling simplified analysis and visualization with Illumina Connected Multiomics and the DRAGEN™ Protein Quantification pipeline, available locally or on the cloud.

 

Is there any difference between using antibody-based vs. aptamer-based technology for NGS-based proteomics?

SOMAmer® reagents in Illumina Protein Prep use aptamers which are 10x smaller than antibodies, enabling better access to targets with ultra-high multiplexing capabilities while eliminating the potential for cross-reactivity. As a result, even minute changes in protein expression can be profiled accurately.

 

Advancing high throughput proteomics - eBook

In this eBook, explore how protein detection technology has evolved and why should you consider adopting NGS-based proteomics to expand the scope of your multiomics study.​
 

  • Why adopt proteomics?
  • Key applications of high-plex proteomics
  • Evolution of proteomics technology
  • NGS-based proteomics as an enabling tool
  • High-impact research studies using SOMAmer Reagents for protein detection
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Educational resources ​to learn more

Podcast
From DNA to Proteins: Illumina Makes Its Proteomics Play, with Krishna Morampudi​​​
Podcast
From DNA to Proteins: Illumina Makes Its Proteomics Play, with Krishna Morampudi​​​​​
In this episode of Mendelspod podcast, Theral Timpson speaks to Krishna Morampudi from Illumina, about the recent definitive agreement to acquire SomaLogic and the launch of Illumina Protein Prep, a new end-to-end, NGS-based, high-throughput proteomics solution.
Article
A New Proteomics Assay Bridges the Gap between Genotype and Phenotype​
Article
A New Proteomics Assay Bridges the Gap between Genotype and Phenotype
Proteomics can connect genotype to phenotype, revealing activity at the molecular level, facilitating the elucidation of disease mechanisms, identification of novel drug targets, and discovery of biomarkers. Learn more about the new NGS-based solution for protein detection in this article from Genetic Engineering News.
On Demand Webinar
Proteomics in Rare Disease using Illumina Protein Prep​
On Demand Webinar
Proteomics in Rare Disease using Illumina Protein Prep
Presentation by Matt Brown describing the Proteomics in Rare Disease Research Program at Genomics England using Illumina Protein Prep and an introduction to this solution designed for NGS-based protein profiling by Nithya Subramanian (Illumina R&D). On demand recording from 2025 Illumina Innovation Event.

Streamline Proteomics Data Analysis with Confidence

Say goodbye to noisy data and hello to high-confidence results. Discover how Illumina Protein Prep and the DRAGEN™ Protein Quantification pipeline deliver high-throughput, normalized protein data with minimal variability. Whether you're chasing new biomarkers or diving deep into the proteome, this streamlined solution will help you get there faster.​ ​

Read the tech note to learn more.​​

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